2-(N,N-Dimethylamino)pyridine-5-boronic acid dihydrochloride

95%

  • Product Code: 218892
  CAS:    265664-54-8
Molecular Weight: 238.91 g./mol Molecular Formula: C₇H₁₁BN₂O₂·₂HCl
EC Number: MDL Number: MFCD07189461
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, dry, sealed
Product Description: Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of pharmaceuticals and biologically active compounds. Its boronic acid functionality enables efficient carbon-carbon bond formation under mild conditions. Commonly employed in the development of kinase inhibitors and other drug candidates due to the presence of the dimethylaminopyridine moiety, which can enhance binding affinity and solubility. Also utilized in the preparation of fluorescent probes and sensors, where the amine group allows for further functionalization and the boronic acid acts as a recognition site for diols in sugars. Stable in solid form and compatible with a variety of reaction conditions, making it suitable for automated and high-throughput synthesis in medicinal chemistry.
Sizes / Availability / Pricing:
Size Availability Price Quantity
1g 10-20 days $608.90
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2-(N,N-Dimethylamino)pyridine-5-boronic acid dihydrochloride
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of pharmaceuticals and biologically active compounds. Its boronic acid functionality enables efficient carbon-carbon bond formation under mild conditions. Commonly employed in the development of kinase inhibitors and other drug candidates due to the presence of the dimethylaminopyridine moiety, which can enhance binding affinity and solubility. Also utilized in the preparation of fluorescent probes and sensors, where the amine group allows for further functionalization and the boronic acid acts as a recognition site for diols in sugars. Stable in solid form and compatible with a variety of reaction conditions, making it suitable for automated and high-throughput synthesis in medicinal chemistry.
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