N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)-1-(14-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-2-oxo-6,9,12-trioxa-3-azatetradecyl)piperidine-4-carboxamide
≥98%
- Product Code: 220465
CAS:
2139287-33-3
| Molecular Weight: | 869.02 g./mol | Molecular Formula: | C₄₀H₅₂N₈O₁₀S₂ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C, Sealed, Drying, Inert Gas |
Product Description:
Used as a linker in antibody-drug conjugates (ADCs) for targeted cancer therapy. It enables controlled delivery of cytotoxic agents to tumor cells by combining the specificity of monoclonal antibodies with potent small-molecule drugs. Its structure supports stable circulation in the bloodstream while allowing efficient release of the active compound inside target cells. The polyethylene glycol (PEG) segments enhance solubility and reduce immunogenicity, improving pharmacokinetic properties. Commonly applied in research and development of novel oncology therapeutics, particularly in PROTAC and targeted degradation technologies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 25mg | 10-20 days | ฿34,160.00 |
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| 50mg | 10-20 days | ฿61,500.00 |
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N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)-1-(14-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-2-oxo-6,9,12-trioxa-3-azatetradecyl)piperidine-4-carboxamide
Used as a linker in antibody-drug conjugates (ADCs) for targeted cancer therapy. It enables controlled delivery of cytotoxic agents to tumor cells by combining the specificity of monoclonal antibodies with potent small-molecule drugs. Its structure supports stable circulation in the bloodstream while allowing efficient release of the active compound inside target cells. The polyethylene glycol (PEG) segments enhance solubility and reduce immunogenicity, improving pharmacokinetic properties. Commonly applied in research and development of novel oncology therapeutics, particularly in PROTAC and targeted degradation technologies.
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