N-(Tert-butoxycarbonyl)-3,3,3-trifluoroalanine

98%

  • Product Code: 220854
  CAS:    188030-43-5
Molecular Weight: 243.18 g./mol Molecular Formula: C₈H₁₂F₃NO₄
EC Number: MDL Number: MFCD10697680
Melting Point: Boiling Point: 303.8±42.0 °C(Predicted)
Density: 1.319±0.06 g/cm3(Predicted) Storage Condition: 2-8°C, Sealed
Product Description: Widely used in peptide synthesis as a protected amino acid building block. The tert-butoxycarbonyl (Boc) group provides acid-labile protection for the amine functionality, allowing selective deprotection under mild acidic conditions without affecting other sensitive groups in complex peptide chains. The presence of trifluoromethyl group enhances metabolic stability and lipophilicity, making this derivative valuable in the development of pharmaceuticals, particularly in medicinal chemistry for designing protease inhibitors and bioactive peptides with improved pharmacokinetic properties. Commonly employed in solid-phase and solution-phase synthesis for constructing fluorinated peptides used in drug discovery and biochemical research.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days ฿26,720.00
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-
250mg 10-20 days ฿37,910.00
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-
N-(Tert-butoxycarbonyl)-3,3,3-trifluoroalanine
Widely used in peptide synthesis as a protected amino acid building block. The tert-butoxycarbonyl (Boc) group provides acid-labile protection for the amine functionality, allowing selective deprotection under mild acidic conditions without affecting other sensitive groups in complex peptide chains. The presence of trifluoromethyl group enhances metabolic stability and lipophilicity, making this derivative valuable in the development of pharmaceuticals, particularly in medicinal chemistry for designing protease inhibitors and bioactive peptides with improved pharmacokinetic properties. Commonly employed in solid-phase and solution-phase synthesis for constructing fluorinated peptides used in drug discovery and biochemical research.
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