OTS964
10mM in DMSO
- Product Code: 221269
CAS:
1338545-07-5
| Molecular Weight: | 428.97 g./mol | Molecular Formula: | C₂₃H₂₄N₂O₂S·HCl |
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| EC Number: | MDL Number: | MFCD28386220 | |
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| Density: | Storage Condition: | -20°C |
Product Description:
OTS964 is a potent inhibitor of the aurora B kinase enzyme, which plays a critical role in cell division and mitosis. It is primarily investigated for its anticancer properties, especially in the treatment of solid tumors and hematological malignancies. By inhibiting aurora B, OTS964 disrupts proper chromosome alignment and cytokinesis, leading to polyploidy and eventual cancer cell death. This makes it a promising candidate for targeted cancer therapy, particularly in tumors with high rates of cell proliferation. Research has shown activity against lung, ovarian, and colon cancer models, among others. Due to its mechanism, OTS964 is also used as a research tool to study mitotic processes and the role of aurora kinases in tumor development. Its development highlights the potential of kinase inhibitors in precision oncology.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿7,200.00 |
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OTS964
OTS964 is a potent inhibitor of the aurora B kinase enzyme, which plays a critical role in cell division and mitosis. It is primarily investigated for its anticancer properties, especially in the treatment of solid tumors and hematological malignancies. By inhibiting aurora B, OTS964 disrupts proper chromosome alignment and cytokinesis, leading to polyploidy and eventual cancer cell death. This makes it a promising candidate for targeted cancer therapy, particularly in tumors with high rates of cell proliferation. Research has shown activity against lung, ovarian, and colon cancer models, among others. Due to its mechanism, OTS964 is also used as a research tool to study mitotic processes and the role of aurora kinases in tumor development. Its development highlights the potential of kinase inhibitors in precision oncology.
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