O, O'-Bis(trimethylsilyl)-5-fluorouracil
98%
- Product Code: 222228
CAS:
17242-85-2
| Molecular Weight: | 274.44 g./mol | Molecular Formula: | C₁₀H₁₉FN₂O₂Si₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00042441 | |
| Melting Point: | Boiling Point: | 114 °C | |
| Density: | 1.05 g/cm3 at 20 °C | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
Used as a silylating agent in the synthesis of fluorinated pyrimidine derivatives, particularly in nucleoside chemistry. Enhances lipophilicity of fluorouracil, improving membrane permeability in prodrug strategies for anticancer agents. Commonly employed in the preparation of intermediates for antiviral and antitumor drugs, especially in solid-phase oligonucleotide synthesis where protection of polar functional groups is required. Also utilized in analytical chemistry to derivatize fluorouracil for improved detection in gas chromatography-mass spectrometry (GC-MS) due to increased volatility and thermal stability.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1g | 10-20 days | ฿1,790.00 |
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| 5g | 10-20 days | ฿4,710.00 |
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| 25g | 10-20 days | ฿21,020.00 |
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O, O'-Bis(trimethylsilyl)-5-fluorouracil
Used as a silylating agent in the synthesis of fluorinated pyrimidine derivatives, particularly in nucleoside chemistry. Enhances lipophilicity of fluorouracil, improving membrane permeability in prodrug strategies for anticancer agents. Commonly employed in the preparation of intermediates for antiviral and antitumor drugs, especially in solid-phase oligonucleotide synthesis where protection of polar functional groups is required. Also utilized in analytical chemistry to derivatize fluorouracil for improved detection in gas chromatography-mass spectrometry (GC-MS) due to increased volatility and thermal stability.
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