4-Oxo-4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amino)butanoic acid
96%
- Product Code: 222363
CAS:
480424-98-4
| Molecular Weight: | 319.16 g./mol | Molecular Formula: | C₁₆H₂₂BNO₅ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD03789267 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, sealed, dry, inert gas |
Product Description:
Used primarily as an intermediate in the synthesis of pharmaceutical compounds, especially in the development of kinase inhibitors for cancer treatment. Its boronic ester functionality enables participation in Suzuki-Miyaura cross-coupling reactions, making it valuable in constructing biaryl systems found in bioactive molecules. It is also employed in medicinal chemistry for modifying peptide-like structures to enhance binding affinity and metabolic stability. Additionally, it serves as a building block in the preparation of proteolysis-targeting chimeras (PROTACs) due to its ability to link target-binding ligands with E3 ligase recruiters.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 250mg | 10-20 days | ฿1,500.00 |
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| 1g | 10-20 days | ฿3,470.00 |
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| 5g | 10-20 days | ฿11,220.00 |
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| 25g | 10-20 days | ฿36,230.00 |
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4-Oxo-4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amino)butanoic acid
Used primarily as an intermediate in the synthesis of pharmaceutical compounds, especially in the development of kinase inhibitors for cancer treatment. Its boronic ester functionality enables participation in Suzuki-Miyaura cross-coupling reactions, making it valuable in constructing biaryl systems found in bioactive molecules. It is also employed in medicinal chemistry for modifying peptide-like structures to enhance binding affinity and metabolic stability. Additionally, it serves as a building block in the preparation of proteolysis-targeting chimeras (PROTACs) due to its ability to link target-binding ligands with E3 ligase recruiters.
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