1-Piperidinesulfonyl fluoride
98%
- Product Code: 222618
CAS:
63698-83-9
| Molecular Weight: | 167.2 g./mol | Molecular Formula: | C₅H₁₀FNO₂S |
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| Density: | Storage Condition: | 2-8°C, Inert Gas |
Product Description:
Used as a highly effective sulfonylating agent in organic synthesis, particularly in the modification of peptides and proteins. It readily reacts with nucleophilic amino acid residues such as serine, threonine, and tyrosine, making it valuable in proteomics research for identifying active sites in enzymes. Commonly employed in chemical biology for activity-based protein profiling (ABPP), enabling the study of enzyme function in complex biological systems. Its stability and selectivity under physiological conditions make it suitable for labeling and inhibiting serine hydrolases and other nucleophilic enzyme families. Also utilized in the development of covalent inhibitors in drug discovery due to its ability to form irreversible bonds with target proteins.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿3,880.00 |
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| 0.250 | 10-20 days | ฿6,340.00 |
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| 1.000 | 10-20 days | ฿17,460.00 |
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1-Piperidinesulfonyl fluoride
Used as a highly effective sulfonylating agent in organic synthesis, particularly in the modification of peptides and proteins. It readily reacts with nucleophilic amino acid residues such as serine, threonine, and tyrosine, making it valuable in proteomics research for identifying active sites in enzymes. Commonly employed in chemical biology for activity-based protein profiling (ABPP), enabling the study of enzyme function in complex biological systems. Its stability and selectivity under physiological conditions make it suitable for labeling and inhibiting serine hydrolases and other nucleophilic enzyme families. Also utilized in the development of covalent inhibitors in drug discovery due to its ability to form irreversible bonds with target proteins.
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