vc-PABC-DM1
99%
- Product Code: 223189
CAS:
1416792-90-9
| Molecular Weight: | 1099.73 g./mol | Molecular Formula: | C₅₃H₇₅ClN₈O₁₃S |
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in antibody-drug conjugates (ADCs) as a linker-payload system, enabling targeted delivery of the potent cytotoxic agent DM1 to cancer cells. The vc-PABC component acts as a cleavable linker that releases DM1 inside the cell after internalization, enhancing therapeutic specificity and reducing systemic toxicity. This construct is particularly effective in tumor-selective drug activation, making it valuable in the development of precision oncology treatments.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1mg | 10-20 days | $5,595.64 |
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vc-PABC-DM1
Used in antibody-drug conjugates (ADCs) as a linker-payload system, enabling targeted delivery of the potent cytotoxic agent DM1 to cancer cells. The vc-PABC component acts as a cleavable linker that releases DM1 inside the cell after internalization, enhancing therapeutic specificity and reducing systemic toxicity. This construct is particularly effective in tumor-selective drug activation, making it valuable in the development of precision oncology treatments.
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