PJ34 HCl
10mM in DMSO
- Product Code: 224124
CAS:
344458-15-7
| Molecular Weight: | 331.80 g./mol | Molecular Formula: | C₁₇H₁₇N₃O₂·HCl |
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| Density: | Storage Condition: | -20°C |
Product Description:
Used primarily in scientific research, this compound acts as a potent inhibitor of PARP-1 and PARP-2 enzymes, which play key roles in DNA repair mechanisms. It is widely applied in studies related to cellular responses to DNA damage, particularly in cancer research. By blocking PARP activity, it enhances the cytotoxic effects of DNA-damaging agents, making it useful in exploring combination therapies with chemotherapy or radiation. It has also been investigated in models of ischemia-reperfusion injury, such as in heart attack and stroke, where inhibition of PARP shows protective effects. Additionally, it is used in aging and neurodegeneration studies due to its role in modulating cellular stress pathways. Its application remains limited to laboratory and preclinical settings, with no approved clinical use in humans.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿5,140.00 |
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PJ34 HCl
Used primarily in scientific research, this compound acts as a potent inhibitor of PARP-1 and PARP-2 enzymes, which play key roles in DNA repair mechanisms. It is widely applied in studies related to cellular responses to DNA damage, particularly in cancer research. By blocking PARP activity, it enhances the cytotoxic effects of DNA-damaging agents, making it useful in exploring combination therapies with chemotherapy or radiation. It has also been investigated in models of ischemia-reperfusion injury, such as in heart attack and stroke, where inhibition of PARP shows protective effects. Additionally, it is used in aging and neurodegeneration studies due to its role in modulating cellular stress pathways. Its application remains limited to laboratory and preclinical settings, with no approved clinical use in humans.
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