Picropodophyllotoxin
10mM in DMSO
- Product Code: 224176
CAS:
477-47-4
| Molecular Weight: | 414.41 g./mol | Molecular Formula: | C₂₂H₂₂O₈ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD01742647 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
Used in cancer research due to its ability to inhibit the insulin-like growth factor 1 receptor (IGF-1R), which plays a key role in tumor cell proliferation and survival. Shows potential as an antitumor agent, particularly in studies involving glioblastoma, melanoma, and other solid tumors. Its mechanism involves inducing cell cycle arrest and promoting apoptosis in cancer cells without significant toxicity to normal cells, making it a candidate for targeted cancer therapy development.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿7,200.00 |
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Picropodophyllotoxin
Used in cancer research due to its ability to inhibit the insulin-like growth factor 1 receptor (IGF-1R), which plays a key role in tumor cell proliferation and survival. Shows potential as an antitumor agent, particularly in studies involving glioblastoma, melanoma, and other solid tumors. Its mechanism involves inducing cell cycle arrest and promoting apoptosis in cancer cells without significant toxicity to normal cells, making it a candidate for targeted cancer therapy development.
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