4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
≥95%
- Product Code: 226226
CAS:
21416-67-1
| Molecular Weight: | 268.27 g./mol | Molecular Formula: | C₁₁H₁₆N₄O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00430424 | |
| Melting Point: | Boiling Point: | 583.5°C at 760 mmHg | |
| Density: | 1.32g/cm3 | Storage Condition: | 2-8°C, stored in inert gas |
Product Description:
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of proteolysis-targeting chimeras (PROTACs). It serves as a linker component that connects target-binding ligands to E3 ubiquitin ligase ligands, enabling targeted protein degradation. Its rigid, semi-cyclic structure provides stability and optimal spatial orientation, enhancing the efficiency and selectivity of the resulting degraders. Widely applied in research for cancer therapeutics and neurodegenerative disease drug development.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿6,140.00 |
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| 250mg | 10-20 days | ฿9,200.00 |
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| 1g | 10-20 days | ฿22,970.00 |
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4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of proteolysis-targeting chimeras (PROTACs). It serves as a linker component that connects target-binding ligands to E3 ubiquitin ligase ligands, enabling targeted protein degradation. Its rigid, semi-cyclic structure provides stability and optimal spatial orientation, enhancing the efficiency and selectivity of the resulting degraders. Widely applied in research for cancer therapeutics and neurodegenerative disease drug development.
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