2-(Pyrrolidin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile
96%
- Product Code: 227429
CAS:
1356068-52-4
| Molecular Weight: | 299.18 g./mol | Molecular Formula: | C₁₆H₂₂BN₃O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD16996763 | |
| Melting Point: | Boiling Point: | 461.3±45.0 °C(Predicted) | |
| Density: | 1.15±0.1 g/cm3(Predicted) | Storage Condition: | Room temperature, sealed |
Product Description:
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation with aryl or heteroaryl halides, facilitating the construction of complex nitrogen-containing heterocyclic systems. The nitrile and pyrrolidine functionalities enhance binding selectivity in medicinal chemistry applications, making it valuable in the development of kinase inhibitors and CNS-targeted drugs. Also employed in materials science for designing electron-transport layers in organic electronics due to its stable conjugated structure.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
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| 100mg | 10-20 days | $77.09 |
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| 250mg | 10-20 days | $137.49 |
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| 1g | 10-20 days | $357.62 |
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| 5g | 10-20 days | $1,460.30 |
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2-(Pyrrolidin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation with aryl or heteroaryl halides, facilitating the construction of complex nitrogen-containing heterocyclic systems. The nitrile and pyrrolidine functionalities enhance binding selectivity in medicinal chemistry applications, making it valuable in the development of kinase inhibitors and CNS-targeted drugs. Also employed in materials science for designing electron-transport layers in organic electronics due to its stable conjugated structure.
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