Propargyl-PEG2-CH2COOtBu
98%
- Product Code: 227963
CAS:
1338564-53-6
Molecular Weight: | 258.31 g./mol | Molecular Formula: | C₁₃H₂₂O₅ |
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Density: | Storage Condition: | 2-8°C, Inert Gas |
Product Description:
Used in bioconjugation and pharmaceutical research as a bifunctional linker. The propargyl group enables click chemistry reactions, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC), allowing efficient coupling with azide-containing molecules. The PEG2 spacer improves solubility and provides flexibility, reducing steric hindrance in conjugates. The tert-butyl ester (tBu) group protects a carboxylic acid functionality, which can be deprotected under mild acidic conditions to release a free carboxylic acid for further coupling. Commonly employed in the synthesis of peptide-drug conjugates, antibody-drug linkers, and functionalized surfaces for assays or materials science. Its design supports controlled, stepwise assembly of complex molecular architectures.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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250mg | 10-20 days | ฿8,240.00 |
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Propargyl-PEG2-CH2COOtBu
Used in bioconjugation and pharmaceutical research as a bifunctional linker. The propargyl group enables click chemistry reactions, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC), allowing efficient coupling with azide-containing molecules. The PEG2 spacer improves solubility and provides flexibility, reducing steric hindrance in conjugates. The tert-butyl ester (tBu) group protects a carboxylic acid functionality, which can be deprotected under mild acidic conditions to release a free carboxylic acid for further coupling. Commonly employed in the synthesis of peptide-drug conjugates, antibody-drug linkers, and functionalized surfaces for assays or materials science. Its design supports controlled, stepwise assembly of complex molecular architectures.
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