(R,E)-2-Methyl-N-(2,2,2-trifluoroethylidene)propane-2-sulfinamide

97%

  • Product Code: 228583
  CAS:    1219607-83-6
Molecular Weight: 201.2095 g./mol Molecular Formula: C₆H₁₀NOF₃S
EC Number: MDL Number:
Melting Point: Boiling Point: 189.3±50.0 °C(Predicted)
Density: 1.25±0.1 g/cm3(Predicted) Storage Condition: 2-8°C, sealed, dry
Product Description: Used as a chiral auxiliary in asymmetric synthesis, particularly in the preparation of enantiomerically pure amines and amino acids. Its structure enables efficient stereocontrol during carbon–carbon and carbon–heteroatom bond-forming reactions. Commonly employed in sulfinyl imine chemistry, it reacts with nucleophiles such as organometallic reagents to deliver high diastereoselectivity. After serving its role, the auxiliary can be cleaved under mild acidic conditions, leaving the desired chiral amine intact. Widely applied in pharmaceutical synthesis where stereochemistry is critical for biological activity.
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Size Availability Price Quantity
1.000 10-20 days $301.31
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(R,E)-2-Methyl-N-(2,2,2-trifluoroethylidene)propane-2-sulfinamide
Used as a chiral auxiliary in asymmetric synthesis, particularly in the preparation of enantiomerically pure amines and amino acids. Its structure enables efficient stereocontrol during carbon–carbon and carbon–heteroatom bond-forming reactions. Commonly employed in sulfinyl imine chemistry, it reacts with nucleophiles such as organometallic reagents to deliver high diastereoselectivity. After serving its role, the auxiliary can be cleaved under mild acidic conditions, leaving the desired chiral amine intact. Widely applied in pharmaceutical synthesis where stereochemistry is critical for biological activity.
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