(R)-2-Amino-2-(2-fluoro-5-nitrophenyl)-N-methylpropane-1-sulfonamide

98%

  • Product Code: 228654
  CAS:    1286777-82-9
Molecular Weight: 291.3 g./mol Molecular Formula: C₁₀H₁₄FN₃O₄S
EC Number: MDL Number: MFCD30803396
Melting Point: Boiling Point: 452.1±55.0 °C(Predicted)
Density: 1.416±0.06 g/cm3(Predicted) Storage Condition: 2-8°C, light-proof, inert gas
Product Description: Used as a key chiral intermediate in the synthesis of protease inhibitors, particularly in the development of antiviral drugs. Its stereochemistry enables selective binding to enzyme active sites, enhancing drug efficacy. Commonly employed in the preparation of HCV (hepatitis C virus) NS3/4A protease inhibitors due to its ability to mimic peptide motifs and resist metabolic degradation. The fluorine and nitro groups facilitate structural optimization for improved pharmacokinetics and target affinity.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days ฿34,160.00
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-
1g 10-20 days ฿156,750.00
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-
(R)-2-Amino-2-(2-fluoro-5-nitrophenyl)-N-methylpropane-1-sulfonamide
Used as a key chiral intermediate in the synthesis of protease inhibitors, particularly in the development of antiviral drugs. Its stereochemistry enables selective binding to enzyme active sites, enhancing drug efficacy. Commonly employed in the preparation of HCV (hepatitis C virus) NS3/4A protease inhibitors due to its ability to mimic peptide motifs and resist metabolic degradation. The fluorine and nitro groups facilitate structural optimization for improved pharmacokinetics and target affinity.
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