(R)-3-amino-4-(2,4-difluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one
98%
- Product Code: 229055
CAS:
945261-48-3
| Molecular Weight: | 389.32 g./mol | Molecular Formula: | C₁₆H₁₆F₅N₅O |
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used as a key intermediate in the synthesis of antifungal agents, particularly in the development of novel triazole-based drugs targeting Candida and Aspergillus species. Its structure enables strong binding to fungal lanosterol 14α-demethylase, inhibiting ergosterol biosynthesis. Employed in pharmaceutical research to enhance drug potency and reduce resistance in systemic fungal infections. Also utilized in structure-activity relationship (SAR) studies to optimize antifungal activity and improve pharmacokinetic properties such as metabolic stability and tissue penetration.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 25mg | 10-20 days | $5,721.98 |
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(R)-3-amino-4-(2,4-difluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one
Used as a key intermediate in the synthesis of antifungal agents, particularly in the development of novel triazole-based drugs targeting Candida and Aspergillus species. Its structure enables strong binding to fungal lanosterol 14α-demethylase, inhibiting ergosterol biosynthesis. Employed in pharmaceutical research to enhance drug potency and reduce resistance in systemic fungal infections. Also utilized in structure-activity relationship (SAR) studies to optimize antifungal activity and improve pharmacokinetic properties such as metabolic stability and tissue penetration.
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