1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-((trimethylsilyl)ethynyl)pyrimidine-2,4(1H,3H)-dione
95%
- Product Code: 229131
CAS:
2260774-98-7
| Molecular Weight: | 340.41 g./mol | Molecular Formula: | C₁₄H₂₀N₂O₆Si |
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| EC Number: | MDL Number: | ||
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| Density: | Storage Condition: | 2-8 °C, sealed, dry |
Product Description:
Used in organic synthesis as a protected nucleoside intermediate, particularly in the preparation of modified RNA or DNA analogs. The trimethylsilyl ethynyl group allows for further functionalization via click chemistry or palladium-catalyzed coupling reactions, making it valuable in the development of antisense oligonucleotides, probes for bioconjugation, and nucleic acid therapeutics. Its hydroxyl protection pattern enables selective deprotection and chain elongation in solid-phase synthesis. Commonly employed in medicinal chemistry for constructing oligonucleotide-based drugs and diagnostic tools.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿6,750.00 |
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| 1g | 10-20 days | ฿40,500.00 |
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| bulk | 10-20 days | ฿0.00 |
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| 250mg | 10-20 days | ฿13,500.00 |
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1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-((trimethylsilyl)ethynyl)pyrimidine-2,4(1H,3H)-dione
Used in organic synthesis as a protected nucleoside intermediate, particularly in the preparation of modified RNA or DNA analogs. The trimethylsilyl ethynyl group allows for further functionalization via click chemistry or palladium-catalyzed coupling reactions, making it valuable in the development of antisense oligonucleotides, probes for bioconjugation, and nucleic acid therapeutics. Its hydroxyl protection pattern enables selective deprotection and chain elongation in solid-phase synthesis. Commonly employed in medicinal chemistry for constructing oligonucleotide-based drugs and diagnostic tools.
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