N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)-benzenesulfonamidehydrochloride
97%
- Product Code: 229187
CAS:
187397-18-8
| Molecular Weight: | 649.08 g./mol | Molecular Formula: | C₂₇H₃₂ClF₃N₄O₇S |
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| Density: | Storage Condition: | -20°C, Sealed, Dry |
Product Description:
Used in pharmaceutical research as a potent and selective inhibitor of histone deacetylase (HDAC), particularly HDAC6. This compound shows promise in the development of treatments for cancer due to its ability to induce apoptosis and inhibit tumor cell proliferation. It is also investigated for its potential in neurodegenerative diseases, where modulation of HDAC activity may help restore normal cellular function. Its sulfonamide and trifluoromethyl groups enhance membrane permeability and metabolic stability, making it suitable for in vivo studies. Commonly employed in preclinical assays to evaluate HDAC-targeted therapies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 10mg | 10-20 days | ฿9,170.00 |
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| 25mg | 10-20 days | ฿18,340.00 |
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| 100mg | 10-20 days | ฿50,970.00 |
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N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)-benzenesulfonamidehydrochloride
Used in pharmaceutical research as a potent and selective inhibitor of histone deacetylase (HDAC), particularly HDAC6. This compound shows promise in the development of treatments for cancer due to its ability to induce apoptosis and inhibit tumor cell proliferation. It is also investigated for its potential in neurodegenerative diseases, where modulation of HDAC activity may help restore normal cellular function. Its sulfonamide and trifluoromethyl groups enhance membrane permeability and metabolic stability, making it suitable for in vivo studies. Commonly employed in preclinical assays to evaluate HDAC-targeted therapies.
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