(1R,2S)-1-Amino-1-(4-fluorophenyl)propan-2-ol hydrochloride
95%(HPLC)
- Product Code: 229331
CAS:
2828440-04-4
| Molecular Weight: | 205.66 g./mol | Molecular Formula: | C₉H₁₃ClFNO |
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| Density: | Storage Condition: | Room temperature, seal, inert gas |
Product Description:
Used as a key chiral intermediate in the synthesis of selective serotonin reuptake inhibitors (SSRIs), particularly in the production of antidepressant medications. Its stereochemistry allows for high enantioselectivity in drug synthesis, improving the efficacy and reducing side effects of the final pharmaceutical product. Commonly employed in asymmetric synthesis routes due to its stable amine-alcohol functionality, which readily participates in reductive amination and nucleophilic addition reactions. Also utilized in the preparation of biologically active molecules where fluorinated aromatic moieties enhance metabolic stability and membrane permeability.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | $1,016.97 |
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| 0.250 | 10-20 days | $1,727.66 |
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| 1.000 | 10-20 days | $4,662.40 |
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(1R,2S)-1-Amino-1-(4-fluorophenyl)propan-2-ol hydrochloride
Used as a key chiral intermediate in the synthesis of selective serotonin reuptake inhibitors (SSRIs), particularly in the production of antidepressant medications. Its stereochemistry allows for high enantioselectivity in drug synthesis, improving the efficacy and reducing side effects of the final pharmaceutical product. Commonly employed in asymmetric synthesis routes due to its stable amine-alcohol functionality, which readily participates in reductive amination and nucleophilic addition reactions. Also utilized in the preparation of biologically active molecules where fluorinated aromatic moieties enhance metabolic stability and membrane permeability.
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