Methyl (R)-5-bromo-2-(1-pivalamidoethyl)benzoate
98%
- Product Code: 229369
CAS:
223595-13-9
| Molecular Weight: | 342.23 g./mol | Molecular Formula: | C₁₅H₂₀BrNO₃ |
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| Density: | Storage Condition: | Room temperature, seal, dry |
Product Description:
Used as a key chiral intermediate in the synthesis of angiotensin II receptor blockers (ARBs), particularly in the production of antihypertensive drugs like valsartan and related analogs. Its stereochemistry allows for selective interaction in biological systems, enhancing drug efficacy. The pivalamido group acts as a protecting group and influences solubility and stability during synthesis. The bromine functionality enables further cross-coupling reactions, facilitating the construction of complex molecular architectures in pharmaceutical development. Commonly employed in multi-step organic syntheses requiring high enantiomeric purity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 250mg | 10-20 days | ฿5,640.00 |
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| 1g | 10-20 days | ฿15,200.00 |
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Methyl (R)-5-bromo-2-(1-pivalamidoethyl)benzoate
Used as a key chiral intermediate in the synthesis of angiotensin II receptor blockers (ARBs), particularly in the production of antihypertensive drugs like valsartan and related analogs. Its stereochemistry allows for selective interaction in biological systems, enhancing drug efficacy. The pivalamido group acts as a protecting group and influences solubility and stability during synthesis. The bromine functionality enables further cross-coupling reactions, facilitating the construction of complex molecular architectures in pharmaceutical development. Commonly employed in multi-step organic syntheses requiring high enantiomeric purity.
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