RN486
10mM in DMSO
- Product Code: 229671
CAS:
1242156-23-5
| Molecular Weight: | 606.690 g./mol | Molecular Formula: | C₃₅H₃₅FN₆O₃ |
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| Density: | Storage Condition: | -20°C |
Product Description:
RN486 is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK), an enzyme involved in B-cell receptor signaling. It is primarily used in research settings to study B-cell activation and proliferation, particularly in the context of autoimmune diseases and B-cell malignancies. By inhibiting BTK, RN486 effectively blocks downstream signaling pathways that lead to B-cell survival and antibody production, making it a valuable tool for investigating conditions such as rheumatoid arthritis, lupus, and certain leukemias and lymphomas. Its high selectivity allows researchers to dissect BTK-specific effects without significant off-target interference, supporting its use in preclinical studies aimed at validating BTK as a therapeutic target.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿7,200.00 |
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RN486
RN486 is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK), an enzyme involved in B-cell receptor signaling. It is primarily used in research settings to study B-cell activation and proliferation, particularly in the context of autoimmune diseases and B-cell malignancies. By inhibiting BTK, RN486 effectively blocks downstream signaling pathways that lead to B-cell survival and antibody production, making it a valuable tool for investigating conditions such as rheumatoid arthritis, lupus, and certain leukemias and lymphomas. Its high selectivity allows researchers to dissect BTK-specific effects without significant off-target interference, supporting its use in preclinical studies aimed at validating BTK as a therapeutic target.
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