Ripasudil (K-115) hydrochloride dihydrate
10mM in DMSO
- Product Code: 229674
CAS:
887375-67-9
| Molecular Weight: | 395.88 g./mol | Molecular Formula: | C₁₅H₁₈FN₃O₂S·ClH·₂H₂O |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD26960897 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
Used primarily in ophthalmology to treat glaucoma and ocular hypertension by reducing intraocular pressure. It acts as a Rho kinase inhibitor, which enhances aqueous humor outflow through the trabecular meshwork. Its mechanism also promotes relaxation of trabecular meshwork and Schlemm’s canal cells, improving drainage. Due to its anti-fibrotic properties, it may help prevent scarring after glaucoma surgery. Additionally studied for corneal endothelial disorders and Fuchs’ dystrophy, where it supports cell migration and wound healing in the corneal endothelium.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿1,850.00 |
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Ripasudil (K-115) hydrochloride dihydrate
Used primarily in ophthalmology to treat glaucoma and ocular hypertension by reducing intraocular pressure. It acts as a Rho kinase inhibitor, which enhances aqueous humor outflow through the trabecular meshwork. Its mechanism also promotes relaxation of trabecular meshwork and Schlemm’s canal cells, improving drainage. Due to its anti-fibrotic properties, it may help prevent scarring after glaucoma surgery. Additionally studied for corneal endothelial disorders and Fuchs’ dystrophy, where it supports cell migration and wound healing in the corneal endothelium.
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