Roflumilast
99%
- Product Code: 229944
Alias:
3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridyl)-4-(difluoromethoxy)benzamide
CAS:
162401-32-3
Properties:
DMSO: soluble20 mg/mL, clear
Molecular Weight: | 403.21 g./mol | Molecular Formula: | C₁₇H₁₄Cl₂F₂N₂O₃ |
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EC Number: | MDL Number: | ||
Melting Point: | 158°C | Boiling Point: | |
Density: | Storage Condition: | -20°C |
Product Description:
Used primarily in the treatment of severe chronic obstructive pulmonary disease (COPD), this compound helps reduce airway inflammation and prevent disease exacerbations. It acts as a selective inhibitor of phosphodiesterase-4, which increases cyclic AMP levels in inflammatory cells, leading to decreased release of pro-inflammatory mediators. It is particularly beneficial in patients with chronic bronchitis and a history of frequent flare-ups. The compound is administered orally and has shown efficacy in improving lung function and health-related quality of life. It may also have potential in treating other inflammatory conditions such as asthma, psoriasis, and atopic dermatitis, though these uses are less established.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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0.500 | 10-20 days | ฿960.00 |
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1.000 | 10-20 days | ฿1,520.00 |
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25.000 | 10-20 days | ฿22,590.00 |
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5.000 | 10-20 days | ฿5,050.00 |
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Roflumilast
Used primarily in the treatment of severe chronic obstructive pulmonary disease (COPD), this compound helps reduce airway inflammation and prevent disease exacerbations. It acts as a selective inhibitor of phosphodiesterase-4, which increases cyclic AMP levels in inflammatory cells, leading to decreased release of pro-inflammatory mediators. It is particularly beneficial in patients with chronic bronchitis and a history of frequent flare-ups. The compound is administered orally and has shown efficacy in improving lung function and health-related quality of life. It may also have potential in treating other inflammatory conditions such as asthma, psoriasis, and atopic dermatitis, though these uses are less established.
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