(R)-3-Amino-3-(3-(trifluoromethyl)phenyl)propanoic acid

96%

  • Product Code: 230070
  CAS:    793663-51-1
Molecular Weight: 233.19 g./mol Molecular Formula: C₁₀H₁₀F₃NO₂
EC Number: MDL Number: MFCD04113664
Melting Point: Boiling Point: 295.2°C
Density: Storage Condition: 2-8°C
Product Description: Used as a key chiral intermediate in the synthesis of antidiabetic drugs, particularly in the production of DPP-4 inhibitors like sitagliptin. Its stereochemistry plays a critical role in enhancing the drug’s potency and selectivity. The presence of the trifluoromethyl group improves metabolic stability and binding affinity to the target enzyme. Widely employed in pharmaceutical research and development for optimizing active pharmaceutical ingredients (APIs) with improved pharmacokinetic profiles.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.100 10-20 days $38.01
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0.250 10-20 days $57.02
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5.000 10-20 days $783.23
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1.000 10-20 days $223.33
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(R)-3-Amino-3-(3-(trifluoromethyl)phenyl)propanoic acid
Used as a key chiral intermediate in the synthesis of antidiabetic drugs, particularly in the production of DPP-4 inhibitors like sitagliptin. Its stereochemistry plays a critical role in enhancing the drug’s potency and selectivity. The presence of the trifluoromethyl group improves metabolic stability and binding affinity to the target enzyme. Widely employed in pharmaceutical research and development for optimizing active pharmaceutical ingredients (APIs) with improved pharmacokinetic profiles.
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