(R)-3-([1,1'-Biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid
95%
- Product Code: 230121
CAS:
128779-47-5
| Molecular Weight: | 341.4 g./mol | Molecular Formula: | C₂₀H₂₃NO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00191185 | |
| Melting Point: | Boiling Point: | 528.2°C | |
| Density: | Storage Condition: | 2-8°C |
Product Description:
Used as a key chiral intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related sartan-class medications. Its stereochemistry allows for selective interaction with biological targets, enhancing drug efficacy. The Boc-protected amine and carboxylic acid functionalities enable stepwise peptide-like coupling in multi-step organic syntheses, making it valuable in pharmaceutical development for cardiovascular therapies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 250mg | 10-20 days | ฿187.00 |
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| 1g | 10-20 days | ฿670.00 |
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| 5g | 10-20 days | ฿2,970.00 |
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| 25g | 10-20 days | ฿14,520.00 |
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(R)-3-([1,1'-Biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid
Used as a key chiral intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related sartan-class medications. Its stereochemistry allows for selective interaction with biological targets, enhancing drug efficacy. The Boc-protected amine and carboxylic acid functionalities enable stepwise peptide-like coupling in multi-step organic syntheses, making it valuable in pharmaceutical development for cardiovascular therapies.
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