RO-9187
≥98%
- Product Code: 230330
CAS:
876708-03-1
| Molecular Weight: | 284.23 g./mol | Molecular Formula: | C₉H₁₂N₆O₅ |
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| Density: | Storage Condition: | 2-8℃ |
Product Description:
RO-9187 is a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK9, which plays a key role in transcriptional regulation. Its primary application lies in cancer research, where it is used to study the inhibition of tumor cell proliferation by disrupting RNA polymerase II-dependent transcription. Due to its ability to induce apoptosis in leukemia and other cancer cell lines, RO-9187 serves as a valuable tool compound in preclinical studies exploring CDK-targeted therapies. It is also used to investigate the role of CDK9 in viral replication, including HIV, where CDK9 is a component of the positive transcription elongation factor b (P-TEFb). This makes RO-9187 relevant in antiviral research as well.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 5mg | 10-20 days | £645.95 |
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| 10mg | 10-20 days | £845.43 |
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RO-9187
RO-9187 is a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK9, which plays a key role in transcriptional regulation. Its primary application lies in cancer research, where it is used to study the inhibition of tumor cell proliferation by disrupting RNA polymerase II-dependent transcription. Due to its ability to induce apoptosis in leukemia and other cancer cell lines, RO-9187 serves as a valuable tool compound in preclinical studies exploring CDK-targeted therapies. It is also used to investigate the role of CDK9 in viral replication, including HIV, where CDK9 is a component of the positive transcription elongation factor b (P-TEFb). This makes RO-9187 relevant in antiviral research as well.
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