(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((3-nitropyridin-2-yl)disulfanyl)propanoic acid
95%
- Product Code: 231260
CAS:
159700-51-3
| Molecular Weight: | 497.55 g./mol | Molecular Formula: | C₂₃H₁₉N₃O₆S₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00065638 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, dry |
Product Description:
Used in peptide synthesis as a specialized protecting group reagent, particularly for cysteine residues. The 3-nitropyridin-2-yl disulfide moiety enables mild and selective disulfide bond formation, which is critical in the preparation of structurally complex peptides and proteins. Its Fmoc group allows compatibility with standard solid-phase peptide synthesis (SPPS), enabling stepwise assembly under basic conditions while preserving the disulfide functionality. This compound is especially valuable in the development of therapeutic peptides where precise disulfide pairing is required for biological activity. It supports efficient monitoring of disulfide bond formation due to the chromogenic properties of the released 3-nitropyridinethione byproduct, which can be detected spectrophotometrically.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿9,350.00 |
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| 250mg | 10-20 days | ฿15,490.00 |
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(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((3-nitropyridin-2-yl)disulfanyl)propanoic acid
Used in peptide synthesis as a specialized protecting group reagent, particularly for cysteine residues. The 3-nitropyridin-2-yl disulfide moiety enables mild and selective disulfide bond formation, which is critical in the preparation of structurally complex peptides and proteins. Its Fmoc group allows compatibility with standard solid-phase peptide synthesis (SPPS), enabling stepwise assembly under basic conditions while preserving the disulfide functionality. This compound is especially valuable in the development of therapeutic peptides where precise disulfide pairing is required for biological activity. It supports efficient monitoring of disulfide bond formation due to the chromogenic properties of the released 3-nitropyridinethione byproduct, which can be detected spectrophotometrically.
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| Stable in pH range | - |
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