rel-1-((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid
98%
- Product Code: 231281
CAS:
1881221-47-1
| Molecular Weight: | 441.52 g./mol | Molecular Formula: | C₂₂H₃₅NO₈ |
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| EC Number: | MDL Number: | ||
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| Density: | Storage Condition: | -20°C, Inert Gas |
Product Description:
Used in pharmaceutical research as a linker in antibody-drug conjugates (ADCs), enabling targeted delivery of cytotoxic agents to cancer cells. Its structure allows for stable attachment to antibodies while maintaining efficient release of the active drug inside the target cell. The polyether chain enhances solubility and reduces aggregation, improving pharmacokinetic properties. Additionally, the strained alkyne in the bicyclic core can participate in bioorthogonal reactions, making it useful for site-specific conjugation in complex biological environments.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 50mg | 10-20 days | ฿7,150.00 |
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| 100mg | 10-20 days | ฿11,400.00 |
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| 250mg | 10-20 days | ฿21,000.00 |
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rel-1-((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid
Used in pharmaceutical research as a linker in antibody-drug conjugates (ADCs), enabling targeted delivery of cytotoxic agents to cancer cells. Its structure allows for stable attachment to antibodies while maintaining efficient release of the active drug inside the target cell. The polyether chain enhances solubility and reduces aggregation, improving pharmacokinetic properties. Additionally, the strained alkyne in the bicyclic core can participate in bioorthogonal reactions, making it useful for site-specific conjugation in complex biological environments.
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