(R)-4-(tert-Butyl)-2-(2-chloro-6-(diphenylphosphaneyl)phenyl)-4,5-dihydrooxazole

97%

  • Product Code: 231383
  CAS:    2757082-51-0
Molecular Weight: 421.8989 g./mol Molecular Formula: C₂₅H₂₅ClNOP
EC Number: MDL Number:
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Density: Storage Condition: 2-8°C, light-proof, inert gas
Product Description: Used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions such as rhodium- or ruthenium-mediated enantioselective hydrogenations. Its phosphine-oxazoline structure provides excellent stereocontrol, making it valuable in the synthesis of optically active pharmaceuticals and fine chemicals. The bulky tert-butyl and diphenylphosphine groups enhance steric and electronic tuning, improving catalyst selectivity and activity. Commonly employed in the production of chiral intermediates for drugs and agrochemicals where high enantiomeric excess is required.
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0.100 10-20 days $51.62
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(R)-4-(tert-Butyl)-2-(2-chloro-6-(diphenylphosphaneyl)phenyl)-4,5-dihydrooxazole
Used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions such as rhodium- or ruthenium-mediated enantioselective hydrogenations. Its phosphine-oxazoline structure provides excellent stereocontrol, making it valuable in the synthesis of optically active pharmaceuticals and fine chemicals. The bulky tert-butyl and diphenylphosphine groups enhance steric and electronic tuning, improving catalyst selectivity and activity. Commonly employed in the production of chiral intermediates for drugs and agrochemicals where high enantiomeric excess is required.
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