Rel-2-((1R,3R,4’’S,5R,5’S,7R)-Dispiro[Adamantane-2,3’-[1,2,4]Trioxolane-5’,1’’-Cyclohexan]-4’’-Yl)Acetic Acid

95%

  • Product Code: 231514
  CAS:    774597-74-9
Molecular Weight: 322.4 g./mol Molecular Formula: C₁₈H₂₆O₅
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: Room temperature
Product Description: Used in antimalarial drug development due to its structural similarity to artemisinin derivatives. The compound acts as a synthetic peroxide, generating reactive oxygen species when exposed to iron in malaria-infected red blood cells, leading to parasite death. Its spirocyclic framework enhances stability and bioavailability, making it a key scaffold in designing next-generation antimalarials with improved resistance profiles. Also explored for antiviral and anticancer applications owing to its selective cytotoxicity under oxidative stress conditions.
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Size Availability Price Quantity
0.100 10-20 days ฿169,600.00
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Rel-2-((1R,3R,4’’S,5R,5’S,7R)-Dispiro[Adamantane-2,3’-[1,2,4]Trioxolane-5’,1’’-Cyclohexan]-4’’-Yl)Acetic Acid
Used in antimalarial drug development due to its structural similarity to artemisinin derivatives. The compound acts as a synthetic peroxide, generating reactive oxygen species when exposed to iron in malaria-infected red blood cells, leading to parasite death. Its spirocyclic framework enhances stability and bioavailability, making it a key scaffold in designing next-generation antimalarials with improved resistance profiles. Also explored for antiviral and anticancer applications owing to its selective cytotoxicity under oxidative stress conditions.
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