(R)-Methyl 5-(6-(Pivaloyloxymethyl)-1H-Benzo[D]Imidazol-1-Yl)-3-(1-(2-(Trifluoromethyl)Phenyl)Ethoxy)Thiophene-2-Carboxylate
98%
- Product Code: 231581
CAS:
929095-38-5
| Molecular Weight: | 560.58 g./mol | Molecular Formula: | C₂₈H₂₇F₃N₂O₅S |
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| EC Number: | MDL Number: | ||
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used as an intermediate in the synthesis of angiotensin II receptor antagonists for the treatment of hypertension. Shows high efficacy in blocking the AT1 receptor subtype, contributing to reduced blood pressure. Its structure allows for improved metabolic stability and oral bioavailability in pharmaceutical formulations. Employed in the development of prodrugs due to the presence of ester and pivaloyloxymethyl groups, which enhance intestinal absorption and facilitate in vivo hydrolysis to the active form. Also investigated for use in combination therapies targeting cardiovascular diseases.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿38,290.00 |
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| 0.250 | 10-20 days | ฿63,820.00 |
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(R)-Methyl 5-(6-(Pivaloyloxymethyl)-1H-Benzo[D]Imidazol-1-Yl)-3-(1-(2-(Trifluoromethyl)Phenyl)Ethoxy)Thiophene-2-Carboxylate
Used as an intermediate in the synthesis of angiotensin II receptor antagonists for the treatment of hypertension. Shows high efficacy in blocking the AT1 receptor subtype, contributing to reduced blood pressure. Its structure allows for improved metabolic stability and oral bioavailability in pharmaceutical formulations. Employed in the development of prodrugs due to the presence of ester and pivaloyloxymethyl groups, which enhance intestinal absorption and facilitate in vivo hydrolysis to the active form. Also investigated for use in combination therapies targeting cardiovascular diseases.
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