(R)-INCB054329
98%
- Product Code: 231904
CAS:
1628607-63-5
| Molecular Weight: | 348.36 g./mol | Molecular Formula: | C₁₉H₁₆N₄O₃ |
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in the treatment of myelofibrosis, a type of bone marrow disorder, (R)-INCB054329 acts as a selective inhibitor of Janus kinase 2 (JAK2), particularly targeting the JAK2V617F mutant form commonly associated with myeloproliferative neoplasms. By inhibiting JAK-STAT signaling, it helps reduce spleen enlargement, alleviate symptoms such as fatigue and night sweats, and improve overall quality of life in patients. It has been studied in clinical trials as part of targeted therapy regimens, often showing improved selectivity and reduced side effects compared to earlier JAK inhibitors. Its development supports the advancement of chiral-specific therapeutics in oncology.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 5mg | 10-20 days | ฿70,000.00 |
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(R)-INCB054329
Used in the treatment of myelofibrosis, a type of bone marrow disorder, (R)-INCB054329 acts as a selective inhibitor of Janus kinase 2 (JAK2), particularly targeting the JAK2V617F mutant form commonly associated with myeloproliferative neoplasms. By inhibiting JAK-STAT signaling, it helps reduce spleen enlargement, alleviate symptoms such as fatigue and night sweats, and improve overall quality of life in patients. It has been studied in clinical trials as part of targeted therapy regimens, often showing improved selectivity and reduced side effects compared to earlier JAK inhibitors. Its development supports the advancement of chiral-specific therapeutics in oncology.
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