(S)-3-((tert-Butoxycarbonyl)amino)-3-(3,4-dichlorophenyl)propanoic acid

95%

  • Product Code: 232427
  CAS:    1241681-36-6
Molecular Weight: 334.2 g./mol Molecular Formula: C₁₄H₁₇Cl₂NO₄
EC Number: MDL Number:
Melting Point: Boiling Point: 475.8±45.0 °C(Predicted)
Density: 1.321±0.06 g/cm3(Predicted) Storage Condition: Room temperature, seal, dry
Product Description: Used as a key chiral intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related sartan-class medications. Its stereochemistry enables selective interaction with biological targets, improving drug efficacy and reducing side effects. Commonly employed in pharmaceutical research and development for constructing peptidomimetic structures due to the protected amine and carboxylic acid functionalities, allowing for sequential coupling reactions in multi-step syntheses.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days $281.12
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1g 10-20 days $1,286.76
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(S)-3-((tert-Butoxycarbonyl)amino)-3-(3,4-dichlorophenyl)propanoic acid
Used as a key chiral intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related sartan-class medications. Its stereochemistry enables selective interaction with biological targets, improving drug efficacy and reducing side effects. Commonly employed in pharmaceutical research and development for constructing peptidomimetic structures due to the protected amine and carboxylic acid functionalities, allowing for sequential coupling reactions in multi-step syntheses.
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