1-((S)-4-(7-((R)-6-Amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one
98%
- Product Code: 232528
CAS:
2417987-45-0
| Molecular Weight: | 622.06 g./mol | Molecular Formula: | C₂₉H₃₂ClF₄N₇O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 743.4±70.0 °C(Predicted) | |
| Density: | 1.344±0.06 g/cm3(Predicted) | Storage Condition: | -20°C, light-proof, inert gas |
Product Description:
Used as a key intermediate in the synthesis of potent kinase inhibitors, particularly in targeted cancer therapies. Its structure enables selective binding to specific tyrosine kinases involved in tumor growth and proliferation. It is employed in the development of pharmaceuticals for treating non-small cell lung cancer and other solid tumors. The compound's design supports improved metabolic stability and bioavailability in drug formulations. It is also utilized in structure-activity relationship (SAR) studies to optimize inhibitor potency and selectivity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.010 | 10-20 days | ฿7,870.00 |
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| 0.050 | 10-20 days | ฿26,550.00 |
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1-((S)-4-(7-((R)-6-Amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one
Used as a key intermediate in the synthesis of potent kinase inhibitors, particularly in targeted cancer therapies. Its structure enables selective binding to specific tyrosine kinases involved in tumor growth and proliferation. It is employed in the development of pharmaceuticals for treating non-small cell lung cancer and other solid tumors. The compound's design supports improved metabolic stability and bioavailability in drug formulations. It is also utilized in structure-activity relationship (SAR) studies to optimize inhibitor potency and selectivity.
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