(2S)-2-(3,3-difluorocyclobutyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)acetic acid
97%
- Product Code: 232529
CAS:
2349734-08-1
| Molecular Weight: | 387.3759 g./mol | Molecular Formula: | C₂₁H₁₉NO₄F₂ |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 586.7±35.0 °C(Predicted) | |
| Density: | 1.40±0.1 g/cm3(Predicted) | Storage Condition: | Room temperature |
Product Description:
Used in peptide synthesis as a protected amino acid building block, particularly in the preparation of complex organic molecules requiring stereochemical control. The fluorenylmethoxycarbonyl (Fmoc) group enables reversible protection of the amine functionality, allowing stepwise assembly in solid-phase peptide synthesis. The difluorocyclobutyl moiety introduces conformational rigidity and enhances metabolic stability, making this compound valuable in medicinal chemistry for developing bioactive peptides with improved pharmacokinetic properties. Commonly employed in research settings for synthesizing enzyme inhibitors or receptor ligands where fluorination modulates binding affinity and lipophilicity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿12,410.00 |
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| 0.500 | 10-20 days | ฿33,000.00 |
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(2S)-2-(3,3-difluorocyclobutyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)acetic acid
Used in peptide synthesis as a protected amino acid building block, particularly in the preparation of complex organic molecules requiring stereochemical control. The fluorenylmethoxycarbonyl (Fmoc) group enables reversible protection of the amine functionality, allowing stepwise assembly in solid-phase peptide synthesis. The difluorocyclobutyl moiety introduces conformational rigidity and enhances metabolic stability, making this compound valuable in medicinal chemistry for developing bioactive peptides with improved pharmacokinetic properties. Commonly employed in research settings for synthesizing enzyme inhibitors or receptor ligands where fluorination modulates binding affinity and lipophilicity.
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