(S)-3-(3-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)phenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid
95%
- Product Code: 232535
CAS:
959573-13-8
| Molecular Weight: | 516.58 g./mol | Molecular Formula: | C₃₀H₃₂N₂O₆ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD06659131 | |
| Melting Point: | Boiling Point: | 733.2±60.0 °C(Predicted) | |
| Density: | 1.245±0.06 g/cm3(Predicted) | Storage Condition: | 2-8°C, sealed, dry, light-proof |
Product Description:
Widely used in peptide synthesis, this compound serves as a chiral building block for the preparation of complex peptides and peptidomimetics. Its structure incorporates orthogonal protecting groups—Fmoc and Boc—that allow selective deprotection under different conditions, enabling stepwise assembly of peptide chains. The Fmoc group is base-labile and commonly removed with piperidine, while the Boc group is acid-labile, removed under mild acidic conditions like trifluoroacetic acid. This dual protection makes it ideal for solid-phase peptide synthesis (SPPS), especially in automated systems. The aromatic fluorenyl group enhances solubility in organic solvents and provides UV detectability, aiding in reaction monitoring and purification. It is particularly valuable in the synthesis of bioactive peptides, pharmaceutical intermediates, and labeled peptides for research.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | $211.15 |
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| 0.250 | 10-20 days | $358.80 |
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| 1.000 | 10-20 days | $968.83 |
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(S)-3-(3-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)phenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid
Widely used in peptide synthesis, this compound serves as a chiral building block for the preparation of complex peptides and peptidomimetics. Its structure incorporates orthogonal protecting groups—Fmoc and Boc—that allow selective deprotection under different conditions, enabling stepwise assembly of peptide chains. The Fmoc group is base-labile and commonly removed with piperidine, while the Boc group is acid-labile, removed under mild acidic conditions like trifluoroacetic acid. This dual protection makes it ideal for solid-phase peptide synthesis (SPPS), especially in automated systems. The aromatic fluorenyl group enhances solubility in organic solvents and provides UV detectability, aiding in reaction monitoring and purification. It is particularly valuable in the synthesis of bioactive peptides, pharmaceutical intermediates, and labeled peptides for research.
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