(2S,3R)-3-(tert-Butoxy)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]pyrrolidine-2-carboxylic acid
97%
- Product Code: 232617
CAS:
443899-48-7
| Molecular Weight: | 409.49 g./mol | Molecular Formula: | C₂₄H₂₇NO₅ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD22689169 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
Widely used in peptide synthesis and chiral chemistry, this compound serves as a protected pyrrolidine building block with defined stereochemistry. The Fmoc group allows for mild base-labile protection of the amine, compatible with solid-phase peptide synthesis (SPPS), enabling sequential amino acid coupling and deprotection. The tert-butoxy group on the pyrrolidine ring stabilizes intermediates and can be removed under acidic conditions, offering orthogonal protection strategies. Its rigid structure and stereochemical purity make it valuable for constructing peptidomimetics, especially in drug discovery targeting proteases or receptors where conformational constraint enhances activity or selectivity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 50mg | 10-20 days | ฿15,840.00 |
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(2S,3R)-3-(tert-Butoxy)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]pyrrolidine-2-carboxylic acid
Widely used in peptide synthesis and chiral chemistry, this compound serves as a protected pyrrolidine building block with defined stereochemistry. The Fmoc group allows for mild base-labile protection of the amine, compatible with solid-phase peptide synthesis (SPPS), enabling sequential amino acid coupling and deprotection. The tert-butoxy group on the pyrrolidine ring stabilizes intermediates and can be removed under acidic conditions, offering orthogonal protection strategies. Its rigid structure and stereochemical purity make it valuable for constructing peptidomimetics, especially in drug discovery targeting proteases or receptors where conformational constraint enhances activity or selectivity.
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