(2S,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-methylpyrrolidine-2-carboxylic acid
98%
- Product Code: 232631
CAS:
333777-34-7
| Molecular Weight: | 351.4 g./mol | Molecular Formula: | C₂₁H₂₁NO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD32710615 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
Widely used in peptide synthesis as a chiral building block, this compound serves as a protected pyrrolidine derivative that enables stereoselective construction of complex molecules. Its Fmoc group allows for mild base-labile protection, making it compatible with solid-phase peptide synthesis (SPPS). The methyl substitution at the 4-position introduces conformational restraint, which is valuable in designing peptidomimetics with enhanced metabolic stability and target selectivity. It is particularly useful in the development of pharmaceuticals where backbone modification improves bioavailability or receptor binding. Commonly employed in medicinal chemistry for synthesizing enzyme inhibitors and bioactive peptides.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 | 10-20 days | ฿10,730.00 |
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| 0.100 | 10-20 days | ฿18,220.00 |
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| 0.250 | 10-20 days | ฿30,980.00 |
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(2S,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-methylpyrrolidine-2-carboxylic acid
Widely used in peptide synthesis as a chiral building block, this compound serves as a protected pyrrolidine derivative that enables stereoselective construction of complex molecules. Its Fmoc group allows for mild base-labile protection, making it compatible with solid-phase peptide synthesis (SPPS). The methyl substitution at the 4-position introduces conformational restraint, which is valuable in designing peptidomimetics with enhanced metabolic stability and target selectivity. It is particularly useful in the development of pharmaceuticals where backbone modification improves bioavailability or receptor binding. Commonly employed in medicinal chemistry for synthesizing enzyme inhibitors and bioactive peptides.
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