(S)-(-)-Tolvaptan

  • Product Code: 232752
  CAS:    331947-44-5
Molecular Weight: 448.94 g./mol Molecular Formula: C₂₆H₂₅ClN₂O₃
EC Number: MDL Number: MFCD30719678
Melting Point: 157-164 °C Boiling Point:
Density: Storage Condition: -20°C
Product Description: Used primarily in the treatment of hyponatremia (low sodium levels in the blood), especially in patients with heart failure, liver cirrhosis, or syndrome of inappropriate antidiuretic hormone secretion (SIADH). It works by blocking the action of vasopressin in the kidneys, promoting the excretion of free water without significant electrolyte loss. This selective V2 receptor antagonism helps increase serum sodium concentration. Also indicated for slowing kidney cyst growth and decline in kidney function in adults with autosomal dominant polycystic kidney disease (ADPKD). Its aquaretic effect makes it valuable in managing fluid overload without causing substantial diuresis of electrolytes.
Sizes / Availability / Pricing:
Size Availability Price Quantity
1mg 10-20 days $2,562.26
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(S)-(-)-Tolvaptan
Used primarily in the treatment of hyponatremia (low sodium levels in the blood), especially in patients with heart failure, liver cirrhosis, or syndrome of inappropriate antidiuretic hormone secretion (SIADH). It works by blocking the action of vasopressin in the kidneys, promoting the excretion of free water without significant electrolyte loss. This selective V2 receptor antagonism helps increase serum sodium concentration. Also indicated for slowing kidney cyst growth and decline in kidney function in adults with autosomal dominant polycystic kidney disease (ADPKD). Its aquaretic effect makes it valuable in managing fluid overload without causing substantial diuresis of electrolytes.
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