(S,E)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-5-hydroxyhept-2-enoic acid

98%

  • Product Code: 232808
  CAS:    1105067-93-3
Molecular Weight: 540.62 g./mol Molecular Formula: C₃₃H₃₃FN₂O₄
EC Number: MDL Number: MFCD34469881
Melting Point: Boiling Point:
Density: Storage Condition: -20°C
Product Description: Used primarily as an active pharmaceutical ingredient in the treatment of hyperlipidemia, particularly for lowering low-density lipoprotein (LDL) cholesterol and reducing cardiovascular risk. It functions as a potent inhibitor of HMG-CoA reductase, the enzyme responsible for a key step in cholesterol biosynthesis in the liver. This inhibition leads to upregulation of LDL receptors, enhancing clearance of LDL from the bloodstream. Commonly prescribed for patients with elevated cholesterol levels, especially those at risk for atherosclerotic cardiovascular disease. Also studied for potential anti-inflammatory and plaque-stabilizing effects in vascular walls. Administered orally, typically once daily, and often part of long-term management strategies in conjunction with diet and lifestyle changes.
Sizes / Availability / Pricing:
Size Availability Price Quantity
1mg 10-20 days €838.29
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(S,E)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-5-hydroxyhept-2-enoic acid
Used primarily as an active pharmaceutical ingredient in the treatment of hyperlipidemia, particularly for lowering low-density lipoprotein (LDL) cholesterol and reducing cardiovascular risk. It functions as a potent inhibitor of HMG-CoA reductase, the enzyme responsible for a key step in cholesterol biosynthesis in the liver. This inhibition leads to upregulation of LDL receptors, enhancing clearance of LDL from the bloodstream. Commonly prescribed for patients with elevated cholesterol levels, especially those at risk for atherosclerotic cardiovascular disease. Also studied for potential anti-inflammatory and plaque-stabilizing effects in vascular walls. Administered orally, typically once daily, and often part of long-term management strategies in conjunction with diet and lifestyle changes.
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