(S)-2-Amino-4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-1-(isoindolin-2-yl)butane-1,4-dione

98%

  • Product Code: 232832
  CAS:    847928-32-9
Molecular Weight: 504.57 g./mol Molecular Formula: C₂₉H₃₀F₂N₄O₂
EC Number: MDL Number: MFCD28167087
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C
Product Description: Used in pharmaceutical research as a key intermediate in the synthesis of proteolysis-targeting chimeras (PROTACs). It functions as a linker component that connects a target protein binder to an E3 ubiquitin ligase recruiter, enabling targeted degradation of disease-related proteins. Its structure supports enhanced cell permeability and stability, making it suitable for developing degraders in oncology and neurodegenerative disease studies. The compound's piperazine and fluorinated aryl groups contribute to favorable binding kinetics and pharmacokinetic properties in preclinical models.
Sizes / Availability / Pricing:
Size Availability Price Quantity
25mg 10-20 days ฿27,110.00
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(S)-2-Amino-4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-1-(isoindolin-2-yl)butane-1,4-dione
Used in pharmaceutical research as a key intermediate in the synthesis of proteolysis-targeting chimeras (PROTACs). It functions as a linker component that connects a target protein binder to an E3 ubiquitin ligase recruiter, enabling targeted degradation of disease-related proteins. Its structure supports enhanced cell permeability and stability, making it suitable for developing degraders in oncology and neurodegenerative disease studies. The compound's piperazine and fluorinated aryl groups contribute to favorable binding kinetics and pharmacokinetic properties in preclinical models.
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