(2S)-2-amino-2-(4,4-difluorocyclohexyl)acetic acidhydrochloride

97%

  • Product Code: 232860
  CAS:    2231665-41-9
Molecular Weight: 229.6521 g./mol Molecular Formula: C₈H₁₄ClF₂NO₂
EC Number: MDL Number: MFCD31697869
Melting Point: Boiling Point:
Density: Storage Condition: Room temperature, inert gas
Product Description: Used in the synthesis of fluorinated analogs of biologically active compounds, particularly in medicinal chemistry for developing CNS-targeted drugs. Its rigid cyclohexyl backbone with geminal difluoro substitution enhances metabolic stability and membrane permeability. Employed as a building block in peptidomimetics and GABA analog derivatives to modulate neurotransmitter activity. The constrained structure helps probe structure-activity relationships in receptor binding studies, especially for ion channels and transporters. Also applied in the design of enzyme inhibitors where steric and electronic effects of fluorine improve selectivity and potency.
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Size Availability Price Quantity
0.100 10-20 days £182.83
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0.250 10-20 days £292.53
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0.500 10-20 days £548.50
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1.000 10-20 days £828.00
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(2S)-2-amino-2-(4,4-difluorocyclohexyl)acetic acidhydrochloride
Used in the synthesis of fluorinated analogs of biologically active compounds, particularly in medicinal chemistry for developing CNS-targeted drugs. Its rigid cyclohexyl backbone with geminal difluoro substitution enhances metabolic stability and membrane permeability. Employed as a building block in peptidomimetics and GABA analog derivatives to modulate neurotransmitter activity. The constrained structure helps probe structure-activity relationships in receptor binding studies, especially for ion channels and transporters. Also applied in the design of enzyme inhibitors where steric and electronic effects of fluorine improve selectivity and potency.
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