(2S)-2-amino-2-(4,4-difluorocyclohexyl)acetic acidhydrochloride
97%
- Product Code: 232860
CAS:
2231665-41-9
Molecular Weight: | 229.6521 g./mol | Molecular Formula: | C₈H₁₄ClF₂NO₂ |
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EC Number: | MDL Number: | MFCD31697869 | |
Melting Point: | Boiling Point: | ||
Density: | Storage Condition: | Room temperature, inert gas |
Product Description:
Used in the synthesis of fluorinated analogs of biologically active compounds, particularly in medicinal chemistry for developing CNS-targeted drugs. Its rigid cyclohexyl backbone with geminal difluoro substitution enhances metabolic stability and membrane permeability. Employed as a building block in peptidomimetics and GABA analog derivatives to modulate neurotransmitter activity. The constrained structure helps probe structure-activity relationships in receptor binding studies, especially for ion channels and transporters. Also applied in the design of enzyme inhibitors where steric and electronic effects of fluorine improve selectivity and potency.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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0.100 | 10-20 days | €211.42 |
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0.250 | 10-20 days | €338.27 |
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0.500 | 10-20 days | €634.25 |
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1.000 | 10-20 days | €957.45 |
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(2S)-2-amino-2-(4,4-difluorocyclohexyl)acetic acidhydrochloride
Used in the synthesis of fluorinated analogs of biologically active compounds, particularly in medicinal chemistry for developing CNS-targeted drugs. Its rigid cyclohexyl backbone with geminal difluoro substitution enhances metabolic stability and membrane permeability. Employed as a building block in peptidomimetics and GABA analog derivatives to modulate neurotransmitter activity. The constrained structure helps probe structure-activity relationships in receptor binding studies, especially for ion channels and transporters. Also applied in the design of enzyme inhibitors where steric and electronic effects of fluorine improve selectivity and potency.
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