(S)-N-(3-Methyl-1-oxo-1-(thiazol-2-ylamino)butan-2-yl)-1H-indole-2-carboxamide
98%
- Product Code: 233218
CAS:
2707510-30-1
| Molecular Weight: | 342.42 g./mol | Molecular Formula: | C₁₇H₁₈N₄O₂S |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | 1.355±0.06 g/cm3(Predicted) | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
Used in pharmaceutical research as a potent and selective inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), an enzyme involved in immune regulation. It modulates the immune response by blocking the metabolism of tryptophan along the kynurenine pathway, thereby preventing immunosuppression in the tumor microenvironment. This makes it a candidate for investigation in cancer immunotherapy, particularly in combination with other immune checkpoint inhibitors. Its (S)-stereochemistry is critical for optimal binding and inhibitory activity. Also employed as a reference compound in biochemical assays to study IDO1 enzyme kinetics and inhibition mechanisms.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1mg | 10-20 days | $309.85 |
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| 5mg | 10-20 days | $926.10 |
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| 10mg | 10-20 days | $1,573.89 |
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| 25mg | 10-20 days | $2,988.75 |
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(S)-N-(3-Methyl-1-oxo-1-(thiazol-2-ylamino)butan-2-yl)-1H-indole-2-carboxamide
Used in pharmaceutical research as a potent and selective inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), an enzyme involved in immune regulation. It modulates the immune response by blocking the metabolism of tryptophan along the kynurenine pathway, thereby preventing immunosuppression in the tumor microenvironment. This makes it a candidate for investigation in cancer immunotherapy, particularly in combination with other immune checkpoint inhibitors. Its (S)-stereochemistry is critical for optimal binding and inhibitory activity. Also employed as a reference compound in biochemical assays to study IDO1 enzyme kinetics and inhibition mechanisms.
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