(S)-2-(4-((((S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid
98%
- Product Code: 233294
CAS:
68538-85-2
| Molecular Weight: | 473.44 g./mol | Molecular Formula: | C₂₀H₂₃N₇O₇ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD31926945 | |
| Melting Point: | Boiling Point: | ||
| Density: | 1.68±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C, light-proof, inert gas |
Product Description:
Used as a key intermediate in the synthesis of antifolate drugs, particularly in the development of targeted cancer therapies. It plays a role in inhibiting enzymes involved in folate metabolism, which is critical for DNA synthesis and cell division in rapidly growing tumor cells. Its structure allows selective binding to folate receptors, making it valuable in designing drugs for cancers that overexpress these receptors, such as ovarian and lung cancers. Also explored in conjugation with antibodies or nanoparticles for improved tumor targeting and reduced systemic toxicity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1mg | 10-20 days | ฿8,110.00 |
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| 5mg | 10-20 days | ฿20,670.00 |
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(S)-2-(4-((((S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid
Used as a key intermediate in the synthesis of antifolate drugs, particularly in the development of targeted cancer therapies. It plays a role in inhibiting enzymes involved in folate metabolism, which is critical for DNA synthesis and cell division in rapidly growing tumor cells. Its structure allows selective binding to folate receptors, making it valuable in designing drugs for cancers that overexpress these receptors, such as ovarian and lung cancers. Also explored in conjugation with antibodies or nanoparticles for improved tumor targeting and reduced systemic toxicity.
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