(S)-3-((tert-Butoxycarbonyl)amino)-3-(2,3-dichlorophenyl)propanoic acid

98%

  • Product Code: 233325
  CAS:    499995-82-3
Molecular Weight: 334.2 g./mol Molecular Formula: C₁₄H₁₇Cl₂NO₄
EC Number: MDL Number: MFCD03427905
Melting Point: Boiling Point: 468.9±45.0 °C(Predicted)
Density: 1.321±0.06 g/cm3(Predicted) Storage Condition: 2-8°C, sealed, dry
Product Description: Used as a key chiral intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related sartan-class medications. Its stereochemistry enables selective binding and improved pharmacokinetic properties in the final drug substance. The Boc-protected amine and carboxylic acid functional groups allow for stepwise peptide-like coupling and deprotection strategies in multi-step organic synthesis. Commonly employed in pharmaceutical research and development for building complex molecules requiring high enantiomeric purity.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days ฿5,060.00
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-
250mg 10-20 days ฿8,600.00
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-
(S)-3-((tert-Butoxycarbonyl)amino)-3-(2,3-dichlorophenyl)propanoic acid
Used as a key chiral intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related sartan-class medications. Its stereochemistry enables selective binding and improved pharmacokinetic properties in the final drug substance. The Boc-protected amine and carboxylic acid functional groups allow for stepwise peptide-like coupling and deprotection strategies in multi-step organic synthesis. Commonly employed in pharmaceutical research and development for building complex molecules requiring high enantiomeric purity.
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