8-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-8-oxooctanoic acid
95%
- Product Code: 233329
CAS:
2172819-75-7
| Molecular Weight: | 586.74 g./mol | Molecular Formula: | C₃₀H₄₂N₄O₆S |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD32903594 | |
| Melting Point: | Boiling Point: | 884.7±65.0 °C(Predicted) | |
| Density: | 1.242±0.06 g/cm3(Predicted) | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
Used in pharmaceutical research as a proteolysis targeting chimera (PROTAC) linker component, enabling targeted protein degradation. Its structure facilitates the connection between an E3 ligase binder and a target protein ligand, promoting ubiquitination and subsequent degradation of disease-related proteins. This compound is particularly valuable in developing therapies for cancer and neurodegenerative diseases by selectively removing pathogenic proteins from cells. It is also employed in biochemical assays to study protein function and validate drug targets.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | $686.27 |
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| 250mg | 10-20 days | $1,165.87 |
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8-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-8-oxooctanoic acid
Used in pharmaceutical research as a proteolysis targeting chimera (PROTAC) linker component, enabling targeted protein degradation. Its structure facilitates the connection between an E3 ligase binder and a target protein ligand, promoting ubiquitination and subsequent degradation of disease-related proteins. This compound is particularly valuable in developing therapies for cancer and neurodegenerative diseases by selectively removing pathogenic proteins from cells. It is also employed in biochemical assays to study protein function and validate drug targets.
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