(4S,5R)-2-((R)-1-(Diphenylphosphanyl)piperidin-2-yl)-4,5-diphenyl-4,5-dihydrooxazole

97%

  • Product Code: 233564
  CAS:    2757084-61-8
Molecular Weight: 490.58 g./mol Molecular Formula: C₃₂H₃₁N₂OP
EC Number: MDL Number:
Melting Point: Boiling Point: 622.1±65.0 °C(Predicted)
Density: Storage Condition: 2-8°C, light-proof, inert gas
Product Description: Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective hydrogenation reactions. It is particularly effective in the reduction of prochiral olefins and ketones, enabling the synthesis of optically active compounds with high enantiomeric excess. Its application is prominent in pharmaceutical manufacturing, where precise stereochemistry is crucial for drug efficacy and safety. The ligand's rigid structure and well-defined chiral environment enhance selectivity and catalytic efficiency when coordinated with transition metals such as iridium or rhodium. It is also employed in the development of fine chemicals and agrochemicals requiring enantiopure intermediates.
Sizes / Availability / Pricing:
Size Availability Price Quantity
50mg 10-20 days ฿7,220.00
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-
100mg 10-20 days ฿11,550.00
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-
250mg 10-20 days ฿19,640.00
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(4S,5R)-2-((R)-1-(Diphenylphosphanyl)piperidin-2-yl)-4,5-diphenyl-4,5-dihydrooxazole
Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective hydrogenation reactions. It is particularly effective in the reduction of prochiral olefins and ketones, enabling the synthesis of optically active compounds with high enantiomeric excess. Its application is prominent in pharmaceutical manufacturing, where precise stereochemistry is crucial for drug efficacy and safety. The ligand's rigid structure and well-defined chiral environment enhance selectivity and catalytic efficiency when coordinated with transition metals such as iridium or rhodium. It is also employed in the development of fine chemicals and agrochemicals requiring enantiopure intermediates.
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