(2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(adamantan-1-yl)acetic acid

95%

  • Product Code: 233566
  CAS:    1221793-29-8
Molecular Weight: 431.52 g./mol Molecular Formula: C₂₇H₂₉NO₄
EC Number: MDL Number: MFCD09952624
Melting Point: Boiling Point: 642.7±38.0 °C(Predicted)
Density: 1.291±0.06 g/cm3(Predicted) Storage Condition: 2-8°C, sealed, dry
Product Description: Widely used in peptide synthesis, this compound serves as a protected amino acid derivative, specifically for introducing adamantyl-containing amino acids into peptide chains. The Fmoc group allows for mild base-labile protection, compatible with solid-phase synthesis strategies. Its bulky adamantyl side chain imparts high hydrophobicity and structural rigidity, making it valuable in the design of conformationally constrained peptides. It is often employed in medicinal chemistry for developing enzyme inhibitors or receptor modulators where steric bulk influences biological activity. Additionally, it finds use in the synthesis of peptidomimetics and bioactive molecules requiring enhanced metabolic stability and membrane permeability.
Sizes / Availability / Pricing:
Size Availability Price Quantity
50mg 10-20 days ฿7,120.00
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100mg 10-20 days ฿11,000.00
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-
250mg 10-20 days ฿19,410.00
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(2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(adamantan-1-yl)acetic acid
Widely used in peptide synthesis, this compound serves as a protected amino acid derivative, specifically for introducing adamantyl-containing amino acids into peptide chains. The Fmoc group allows for mild base-labile protection, compatible with solid-phase synthesis strategies. Its bulky adamantyl side chain imparts high hydrophobicity and structural rigidity, making it valuable in the design of conformationally constrained peptides. It is often employed in medicinal chemistry for developing enzyme inhibitors or receptor modulators where steric bulk influences biological activity. Additionally, it finds use in the synthesis of peptidomimetics and bioactive molecules requiring enhanced metabolic stability and membrane permeability.
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