(S)-2-((R)-1-(Diphenylphosphanyl)piperidin-2-yl)-4-phenyl-4,5-dihydrooxazole
97%
- Product Code: 233567
CAS:
2757084-58-3
| Molecular Weight: | 414.48 g./mol | Molecular Formula: | C₂₆H₂₇N₂OP |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 557.8±60.0 °C(Predicted) | |
| Density: | Storage Condition: | 2-8°C, light-proof, inert gas |
Product Description:
Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective hydrogenation reactions. It is particularly effective in the synthesis of chiral amines and amino acid derivatives, which are important intermediates in pharmaceutical manufacturing. Due to its rigid oxazoline-piperidine backbone and tunable phosphine group, it forms highly selective complexes with transition metals like rhodium and iridium. These catalysts enable high enantiomeric excess (ee) in transformations such as the asymmetric reduction of olefins and imines. Its application is prominent in the production of bioactive molecules where stereochemistry is critical for activity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 50mg | 10-20 days | ฿8,210.00 |
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| 250mg | 10-20 days | ฿22,340.00 |
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| 100mg | 10-20 days | ฿13,970.00 |
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(S)-2-((R)-1-(Diphenylphosphanyl)piperidin-2-yl)-4-phenyl-4,5-dihydrooxazole
Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective hydrogenation reactions. It is particularly effective in the synthesis of chiral amines and amino acid derivatives, which are important intermediates in pharmaceutical manufacturing. Due to its rigid oxazoline-piperidine backbone and tunable phosphine group, it forms highly selective complexes with transition metals like rhodium and iridium. These catalysts enable high enantiomeric excess (ee) in transformations such as the asymmetric reduction of olefins and imines. Its application is prominent in the production of bioactive molecules where stereochemistry is critical for activity.
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